A Study in Iran

OBJECTIVE: To evaluate some of the risk factors of complete molar pregnancy. STUDY DESIGN: A case-control study was performed on 91 cases of complete molar pregnancy (case group) and 295 cases of normal, term pregnancy with a live neonate (control group). Then the maternal age, parity and gravidity, blood group and Rh, history of molar pregnancy, consanguinity, history of spontaneous abortion, contraception method and nationality (Afghan or Iranian) were compared in the 2 groups. RESULTS: History of molar pregnancy (OR [odds ratio], 95% CI 5.7 [1.2–25.6]), spontaneous abortion (OR, 95% CI 2.1 [1.7–2.6]), maternal age > 35 years old (OR, 95% CI 2.3 [1.3–3.9]) and < 20 years old (OR, 95% CI 1.6 [1.4–1.9]), consanguinity (OR, 95% CI 1.3 [1.1–1.5]) and Iranian nationality (OR, 95% CI 1.9 [(1.5–2.4]) were found to be risk factors for molar pregnancy. CONCLUSION: History of molar pregnancy and spontaneous abortion, maternal age > 35 and < 20, consanguinity and nationality may be risk factors for molar pregnancy. (J Reprod Med 2009;54:621–624)